Question:
I WOULD LIKE TO KNOW WHY THE TIME CAPSULE

WHY DONT TIME CAPSULE DONT WORK ON RNY PEOPLE. I HAVE HAD RNY JULY 2005. I TAKE CYMBALTA TIME RELEASE I THOUGHT IT WORKED. I WANT TO EAT BUT I THROW UP A LOT. I HAVENT LOST WT IN A YEAR AND STILL CANT EAT MEAT. 130 POUNDS OFF THOUGH. SHOULD I GOT ON DIET PILL?    — sybiliowa (posted on October 11, 2007)

October 11, 2007
I don't think taking a diet pill would solve your problem or be safe. Losing the weight doesn't seem to be your problem. I also take Cymbalta and know that it can affect your appetite, so I'm wondering if that's part of the problem. Another thought is that maybe it can't be fully absorbed because of the RNY. Just my thoughts, but I think if it were me I'd discuss the Cymbalta issue with whoever prescribed it (I would think they would be familiar with this) and also discuss your concerns with your surgeon. Good luck, and please let me know how you make out.
   — obeseforever

October 11, 2007
I just found this onanother post addressing this same issue but about Effexor XR: The reason time release is less effective (note I didn't say doesn't work) is that with this little pouch we have now, pills and liquid pass relatively quickly, and there is not as much stomach acid to degrade or "use up" your medication. Time release and/or long acting medications work by having an outer coating or capsule that degrades slower in your stomach acid or digestive juices during digestion. Since we WLS patients have 1. smaller stomachs, with 2. Less digestive juices, and 3. our pathway of digestion is altered, these types of long acting medications may have partial to NO absorption for us. This from a recommendation for primary care physicians now caring for post-op bariatric patients: "Clinicians should not prescribe extended-release drugs because reducedtransit times and changed intestinal anatomy influence the amount ofmedication that reaches the bloodstream. In the immediate postoperativeperiod, medications with small therapeutic windows, such as lithium oranticoagulants, should be monitored closely, and dosing changed as indicated.Clinicians should not prescribe nonsteroidal anti-inflammatory agents, whichincrease irritation and bleeding. " Link to this article: http://docnews.diabetesjournals.org/cgi/content/full/3/7/14 Bottom line though hon, work closely with your physicians. They and you, know your case history and should be making the best and appropriate choices for your medications and treatment. Hope this helps!
   — obeseforever